수의과대학 | 교수 및 실험실 | 교수 소개

이름

이진수 (Lee Jinsoo)

전공

실험동물의학

연락처

042-821-6778

학력

학사: 2003-2009, 충북대학교 수의과대학
석사: 2009-2011, 과학기술연합대학원대학교 약리 및 독성평가학
박사: 2017-2021, 충북대학교 수의과대학

경력

- 2010: 방문연구생, 일본 이화학연구소(RIKEN), Bio Resource Center, Japan Mouse Clinic
- 2011-2014: 연구원, 한국화학연구원 부설 안전성평가연구소(Korea Institute of Toxicology)
- 2015-2022: 선임연구원, 한국화학연구원 부설 안전성평가연구소(Korea Institute of Toxicology)
- 2015-현재: 정회원, 미국 선천성기형 연구 및 예방학회(Birth Defects Research and Prevention)
- 2015-현재: 정회원, 유럽 기형학회(European Teratology Society)
- 2016-현재: 한국독성전문가(DKBT, Diplomate of Korean Board of Toxicology)
- 2018-현재: 미국독성전문가(DABT, Diplomate of American Board of Toxicology)
- 2022-현재: 조교수, 충남대학교 수의과대학
- 2023-현재: 부위원장, 한국동물실험대체법학회 편집위원회

관심분야

- 실험동물을 사용한 유해인자의 생식발생/발육기 독성 연구
- 실험동물을 사용한 후보물질의 비임상/규제독성 연구
- 유해인자의 독성기전 연구
- 동물실험 3R(Refinement, Reduction, Replacement) 연구

논문

30.	Lee, J., Han, B. C., Kim, W., Shin, S. H., Jeong, J. S., Yixian, Q., & Yu, W. J. (2024). Juvenile toxicity study of deer antler extract in rats. Journal of Ethnopharmacology, 319, 117094.
29.	Go, H., Lim, Y., Park, J. D., Jeong, J. S., & Lee, J. (2023). Micro-CT as a new method for assessing non-clinical skeletal birth defects. Journal of Alternatives to Animal Experiments, 17(2), 51-58.
28.	Lee, S. J., Baek, S. K., Kim, W., Quah, Y., Kim, S. Y., ... Lee, J & Yu, W. J. (2022). Reproductive and developmental toxicity screening of bisphenol F by oral gavage in rats. Regulatory Toxicology and Pharmacology, 136, 105286.
27.	Moon, K. N., Baek, S. K., Kim, W., Jeong, J. S., Lee, B. S., Quah, Y., Lee, J.... & Yu, W. J. (2022). Prenatal developmental toxicity study of 2, 4-dichlorobenzyl alcohol in rats. Regulatory Toxicology and Pharmacology, 132, 105168.
26.	Lee, J., Jeong, J. S., Kim, S. Y., Kim, W., Lee, S. Y., Park, J. D., ... & Yu, W. J. (2022). Bis-diamine administration during pregnancy induces developmental and reproductive toxicities in rats. Birth Defects Research, 114, 509-524.
25.	Lee, J., Choi, S. J., Jeong, J. S., Kim, S. Y., Lee, S. J., Baek, S. K., ... & Yu, W. J. (2022). Adverse postnatal developmental effects in offspring from humidifier disinfectant biocide inhaled pregnant rats. Chemosphere, 286, 131636.
24.	Lee, J., Jeong, J. S., Kim, W., Kim, S. Y., Lee, S. J., Baek, S. K., ... & Yu, W. J. (2021). Serial blood sampling effects in rat embryo-fetal development studies for toxicokinetics. Regulatory Toxicology and Pharmacology, 123, 104930.
23.	Lee, J., Choi, S. J., Jeong, J. S., Kim, S. Y., Lee, S. H., Yang, M. J., ... & Yu, W. J. (2021). A humidifier disinfectant biocide, polyhexamethylene guanidine phosphate, inhalation exposure during pregnancy induced toxicities in rats. Journal of Hazardous Materials, 404, 124007.
22.	Lee, J., Jeong, J. S., Kim, S. Y., Lee, S. J., Shin, Y. J., Im, W. J., ... & Yu, W. J. (2020). Safety assessment of cerium oxide nanoparticles: Combined repeated-dose toxicity with reproductive/developmental toxicity screening and biodistribution in rats. Nanotoxicology, 14(5), 696-710.
21.	Lee, J., Jeong, J. S., Kim, S. Y., Im, W. J., Shin, Y. J., Lee, K., ... & Yu, W. J. (2019). Reproductive and developmental toxicity screening of polyhexamethylene guanidine phosphate by oral gavage in rats. Regulatory Toxicology and Pharmacology, 108, 104440.
20.	Lee, J., Jeong, J. S., Kim, S. Y., Park, M. K., Choi, S. D., Kim, U. J., ... & Yu, W. J. (2019). Titanium dioxide nanoparticles oral exposure to pregnant rats and its distribution. Particle and fibre toxicology, 16(1), 1-12.
19.	Lee, J., Jeong, J. S., Cho, K. J., Moon, K. N., Kim, S. Y., Han, B., ... & Yu, W. J. (2019). Developmental and reproductive toxicity assessment in rats with KGC-HJ3, Korean Red Ginseng with Angelica gigas and Deer antlers. Journal of ginseng research, 43(2), 242-251.
18.	Park, K., Park, J., Lee, H., Choi, J., Yu, W. J., & Lee, J. (2018). Toxicity and tissue distribution of cerium oxide nanoparticles in rats by two different routes: single intravenous injection and single oral administration. Archives of pharmacal research, 41(11), 1108-1116.
17.	Jeong, J. S., Nam, K. T., Lee, B., Pamungkas, A. D., Song, D., Kim, M., Yu. W. J., Lee. J., ... & Lim, K. M. (2017). Low-Dose Bisphenol A Increases Bile Duct Proliferation in Juvenile Rats: A Possible Evidence for Risk of Liver Cancer in the Exposed Population?. Biomolecules & therapeutics, 25(5), 545.
16.	Lee, J., Yu, W. J., Song, J., Sung, C., Jeong, E. J., Han, J. S., ... & Kwon, J. T. (2016). Developmental toxicity of intravenously injected zinc oxide nanoparticles in rats. Archives of pharmacal research, 39(12), 1682-1692.
15.	Yoon, J. H., Seo, H. S., Lee, J., Moon, C., & Lee, K. (2016). Acute high-level toluene exposure decreases hippocampal neurogenesis in rats. Toxicology and industrial health, 32(11), 1910-1920.
14.	Lee, J., Song, J., Jeong, E. J., Chung, M. K., Hwang, K. H., Koo, S. J., & Yu, W. J. (2015). Developmental toxicity assessment of the new turf herbicide, methiozolin ([5-(2, 6-difluorobenzyl) oxymethyl-5-methyl-3, 3 (3-methylthiophen-2-yl)-1, 2-isoxazoline]), in rabbits. Regulatory Toxicology and Pharmacology, 72(3), 639-645.
13.	Yu, W. J., Son, J. M., Lee, J., Kim, S. H., Lee, I. C., Baek, H. S., ... & Kim, J. C. (2014). Effects of silver nanoparticles on pregnant dams and embryo-fetal development in rats. Nanotoxicology, 8(sup1), 85-91.
12.	Yu, W. J., Lee, I. C., Lee, J., Lee, S. M., Kim, S. H., Baek, H. S., ... & Kim, J. C. (2013). 4-Week repeated oral dose toxicity study of 1, 4-dichlorobutane in rats. Laboratory animal research, 29(1), 48-54.
11.	Chung, M. K., Yu, W. J., Lee, J., & Lee, J. H. (2013). Embryotoxicity and toxicokinetics of the antimalarial artesunate in rats. Toxicological research, 29(1), 27.
10.	Kwon, S., Yang, Y. S., Yang, H. S., Lee, J., Kang, M. S., Lee, B. S., ... & Song, C. W. (2012). Nasal and pulmonary toxicity of titanium dioxide nanoparticles in rats. Toxicological research, 28(4), 217.
9.	Park, D., Bae, D. K., Jeon, J. H., Lee, J., Oh, N., Yang, G., ... & Song, B. S. (2011). Immunopotentiation and antitumor effects of a ginsenoside Rg3-fortified red ginseng preparation in mice bearing H460 lung cancer cells. Environmental toxicology and pharmacology, 31(3), 397-405.
8.	Yang, G., Park, D., Lee, J., Song, B. S., Jeon, T. H., Kang, S. J., ... & Kim, Y. B. (2011). Suppressive effects of red ginseng preparations on SW480 colon cancer xenografts in mice. Food Science and Biotechnology, 20(6), 1649-1653.
7.	Yang, Y. S., Lee, J., Kwon, S., Seo, H. S., Choi, S. J., Yu, H. J., ... & Cho, K. H. (2010). LC50 determination of tert-butyl acetate using a nose only inhalation exposure in rats. Toxicological research, 26(4), 293.
6.	Lee, J., Han, Y. A., Yang, H. S., Song, J. A., Yang, Y. S., Kwon, S., ... & Song, C. W. (2010). The Incidence Rate and Severity of Orthotopic Lung Cancer in an Animal Model Depends on the Number of A549 Cells and Transplantation Period. Laboratory Animal Research, 26(4), 369-375.
5.	Kim, S. N., Lee, J., Yang, H. S., Cho, J. W., Kwon, S., Kim, Y. B., ... & Lee, K. (2010). Dose-response effects of bleomycin on inflammation and pulmonary fibrosis in mice. Toxicological research, 26(3), 217.
4.	Song, J. A., Yang, H. S., Lee, J., Kwon, S., Jung, K. J., Heo, J. D., ... & Lee, K. (2010). Standardization of bronchoalveolar lavage method based on suction frequency number and lavage fraction number using rats. Toxicological research, 26(3), 203.
3.	Ryu, J. M., Kim, T. M., Yeon, S., Lim, W. T., Lee, J. Y., Hwang, S. Y., ... & Lee, J., Kim, Y. B. (2008). Effect of repeated administration of silk peptide on the immune system of rats. Laboratory Animal Research, 24(3), 361-369.
2.	Shin, S., Park, D., Jang, M. J., Jeon, J. H., Namgil, O., Song, J., Lee, J., ... & Kim, Y. B. (2008). Protective effect of anthocyanins against the hepatotoxicity of carbon tetrachloride in rats. Laboratory Animal Research, 24(3), 355-360.
1.	Kim, J. J., Kim, C. W., Park, D., Shin, S., Jeon, J. H., Jang, M. J., Ji, H. J., O, N., Song, J., Lee, J., ... & Kim, B. Y. (2008). Effects of sweet potato fractions on alcoholic hangover and gastric ulcer. Laboratory Animal Research, 24(2), 209-216.